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Discoidin Domain Receptor 2 Signaling Regulates Fibroblast Apoptosis through PDK1/Akt

Progressive fibrosis is a complication of many chronic diseases, and collectively, organ fibrosis is the leading cause of death in the United States. Fibrosis is characterized by accumulation of activated fibroblasts and excessive deposition of extracellular matrix proteins, especially type I collag...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Jia, Shijing, Agarwal, Manisha, Yang, Jibing, Horowitz, Jeffrey C., White, Eric S., Kim, Kevin K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189640/
https://ncbi.nlm.nih.gov/pubmed/29652518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0419OC
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