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Discoidin domain receptors regulate the migration of primary human lung fibroblasts through collagen matrices

BACKGROUND: The two discoidin domain receptors (DDRs), DDR1 and DDR2 are receptor tyrosine kinases (RTKs) with the unique ability among RTKs to respond to collagen. We have previously shown that collagen I induces DDR1 and matrix metalloproteinase (MMP)-10 expression through DDR2 activation and a Ja...

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Detalhes bibliográficos
Main Authors: Ruiz, Pedro A, Jarai, Gabor
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298810/
https://ncbi.nlm.nih.gov/pubmed/22336030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-5-3
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