Wird geladen...

Type I Collagen Signaling Regulates Opposing Fibrotic Pathways through α(2)β(1) Integrin

Fibrosis is characterized by fibroblast activation, leading to matrix remodeling culminating in a stiff, type I collagen–rich fibrotic matrix. Alveolar epithelial cell (AEC) apoptosis is also a major feature of fibrogenesis, and AEC apoptosis is sufficient to initiate a robust lung fibrotic response...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Am J Respir Cell Mol Biol
Hauptverfasser: Agarwal, Manisha, Goheen, Mitchell, Jia, Shijing, Ling, Song, White, Eric S., Kim, Kevin K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605165/
https://ncbi.nlm.nih.gov/pubmed/32692932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2020-0150OC
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!