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NAD(+) Promotes Assembly of the Active Tetramer of Aldehyde Dehydrogenase 7A1

Nicotinamide adenine dinucleotide (NAD) is the redox cofactor of many enzymes, including the vast aldehyde dehydrogenase (ALDH) superfamily. Although the function of NAD(H) in hydride transfer is established, its influence on protein structure is less understood. Herein, we show that NAD(+)-binding...

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Pubblicato in:FEBS Lett
Autori principali: Korasick, David A., White, Tommi A., Chakravarthy, Srinivas, Tanner, John J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188814/
https://ncbi.nlm.nih.gov/pubmed/30184263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13238
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