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Structural Basis of Substrate Recognition by Aldehyde Dehydrogenase 7A1
[Image: see text] Aldehyde dehydrogenase 7A1 (ALDH7A1) is part of lysine catabolism and catalyzes the NAD(+)-dependent oxidation of α-aminoadipate semialdehyde to α-aminoadipate. Herein, we describe a structural study of human ALDH7A1 focused on substrate recognition. Five crystal structures and sma...
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| Publicado no: | Biochemistry |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2015
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4565128/ https://ncbi.nlm.nih.gov/pubmed/26260980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00754 |
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