Importance of the C-Terminus of Aldehyde Dehydrogenase 7A1 for Oligomerization and Catalytic Activity

Aldehyde dehydrogenase 7A1 (ALDH7A1) catalyzes the terminal step of lysine catabolism, the NAD(+)-dependent oxidation of α-aminoadipate semialdehyde to α-aminoadipate. Structures of ALDH7A1 reveal the C-terminus is a gate that opens and closes in response to the binding of α-aminoadipate. In the clo...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Biochemistry
Hlavní autoři: Korasick, David A., Wyatt, Jesse W., Luo, Min, Laciak, Adrian R., Ruddraraju, Kasi, Gates, Kent S., Henzl, Michael T., Tanner, John J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928510/
https://ncbi.nlm.nih.gov/pubmed/29045138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00803
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky