A glutaredoxin domain fused to the radical-generating subunit of ribonucleotide reductase (RNR) functions as an efficient RNR reductant

Class I ribonucleotide reductase (RNR) consists of a catalytic subunit (NrdA) and a radical-generating subunit (NrdB) that together catalyze reduction of ribonucleotides to their corresponding deoxyribonucleotides. NrdB from the firmicute Facklamia ignava is a unique fusion protein with N-terminal a...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Rozman Grinberg, Inna, Lundin, Daniel, Sahlin, Margareta, Crona, Mikael, Berggren, Gustav, Hofer, Anders, Sjöberg, Britt-Marie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2018
Onderwerpen:
Enzymology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187632/
https://ncbi.nlm.nih.gov/pubmed/30166338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004991
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