Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents

[Image: see text] Schistosomiasis is a major human parasitic disease afflicting more than 250 million people, historically treated with chemotherapies praziquantel or oxamniquine. Since oxamniquine is species-specific, killing Schistosoma mansoni but not other schistosome species (S. haematobium or...

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Vydáno v:ACS Med Chem Lett
Hlavní autoři: Rugel, Anastasia, Tarpley, Reid S., Lopez, Ambrosio, Menard, Travis, Guzman, Meghan A., Taylor, Alexander B., Cao, Xiaohang, Kovalskyy, Dmytro, Chevalier, Frédéric D., Anderson, Timothy J. C., Hart, P. John, LoVerde, Philip T., McHardy, Stanton F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2018
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187409/
https://ncbi.nlm.nih.gov/pubmed/30344901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00257
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