Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents

[Image: see text] Schistosomiasis is a major human parasitic disease afflicting more than 250 million people, historically treated with chemotherapies praziquantel or oxamniquine. Since oxamniquine is species-specific, killing Schistosoma mansoni but not other schistosome species (S. haematobium or...

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Bibliografski detalji
Izdano u:ACS Med Chem Lett
Glavni autori: Rugel, Anastasia, Tarpley, Reid S., Lopez, Ambrosio, Menard, Travis, Guzman, Meghan A., Taylor, Alexander B., Cao, Xiaohang, Kovalskyy, Dmytro, Chevalier, Frédéric D., Anderson, Timothy J. C., Hart, P. John, LoVerde, Philip T., McHardy, Stanton F.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2018
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187409/
https://ncbi.nlm.nih.gov/pubmed/30344901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00257
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