Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents

[Image: see text] Schistosomiasis is a major human parasitic disease afflicting more than 250 million people, historically treated with chemotherapies praziquantel or oxamniquine. Since oxamniquine is species-specific, killing Schistosoma mansoni but not other schistosome species (S. haematobium or...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Rugel, Anastasia, Tarpley, Reid S., Lopez, Ambrosio, Menard, Travis, Guzman, Meghan A., Taylor, Alexander B., Cao, Xiaohang, Kovalskyy, Dmytro, Chevalier, Frédéric D., Anderson, Timothy J. C., Hart, P. John, LoVerde, Philip T., McHardy, Stanton F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187409/
https://ncbi.nlm.nih.gov/pubmed/30344901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00257
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