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Cochaperone Mzb1 is a key effector of Blimp1 in plasma cell differentiation and β1-integrin function

Plasma cell differentiation involves coordinated changes in gene expression and functional properties of B cells. Here, we study the role of Mzb1, a Grp94 cochaperone that is expressed in marginal zone (MZ) B cells and during the terminal differentiation of B cells to antibody-secreting cells. By an...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Andreani, Virginia, Ramamoorthy, Senthilkumar, Pandey, Abhinav, Lupar, Ekaterina, Nutt, Stephen L., Lämmermann, Tim, Grosschedl, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187189/
https://ncbi.nlm.nih.gov/pubmed/30257949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1809739115
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