Mzb1 Protein Regulates Calcium Homeostasis, Antibody Secretion, and Integrin Activation in Innate-like B Cells

Marginal zone (MZ) B cells of the spleen and B1 cells, termed innate-like B cells, differ from follicular B cells by their attenuated Ca(2+) mobilization, fast antibody secretion, and increased cell adhesion. We identified and characterized Mzb1 as an endoplasmic reticulum-localized and B cell-speci...

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Bibliografiske detaljer
Main Authors: Flach, Henrik, Rosenbaum, Marc, Duchniewicz, Marlena, Kim, Sola, Zhang, Shenyuan L., Cahalan, Michael D., Mittler, Gerhard, Grosschedl, Rudolf
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125521/
https://ncbi.nlm.nih.gov/pubmed/21093319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.11.013
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