Regulation of Lymphatic GM-CSF Expression by the E3 Ubiquitin Ligase Cbl-b

Genome-wide association studies as well as lymphatic expression analyses have linked both Cbl-b and GM-CSF to human multiple sclerosis as well as other autoimmune diseases. Both Cbl-b and GM-CSF have been shown to play a prominent role in the development of murine encephalomyelitis; however, no func...

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Publicat a:Front Immunol
Autors principals: Peer, Sebastian, Cappellano, Giuseppe, Hermann-Kleiter, Natascha, Albrecht-Schgoer, Karin, Hinterleitner, Reinhard, Baier, Gottfried, Gruber, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186797/
https://ncbi.nlm.nih.gov/pubmed/30349541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02311
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