Role of PKCtheta in macrophage-mediated immune response to Salmonella typhimurium infection in mice

BACKGROUND: The serine/threonine protein kinase C (PKC) theta has been firmly implicated in T cell-mediated immunity. Because its role in macrophages has remained undefined, we employed PKCtheta-deficient (PKCtheta(−/−)) mice in order to investigate if PKCtheta plays a role in macrophage-mediated im...

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Vydáno v:Cell Commun Signal
Hlavní autoři: Pfeifhofer-Obermair, Christa, Albrecht-Schgoer, Karin, Peer, Sebastian, Nairz, Manfred, Siegmund, Kerstin, Klepsch, Victoria, Haschka, David, Thuille, Nikolaus, Hermann-Kleiter, Natascha, Gruber, Thomas, Weiss, Günter, Baier, Gottfried
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964075/
https://ncbi.nlm.nih.gov/pubmed/27465248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-016-0137-y
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