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Protein kinase C theta is dispensable for suppression mediated by CD25(+)CD4(+) regulatory T cells
The activation of conventional T cells upon T cell receptor stimulation critically depends on protein kinase C theta (PKCθ). However, its role in regulatory T (Treg) cell function has yet to be fully elucidated. Using siRNA or the potent and PKC family-selective pharmacological inhibitor AEB071, we...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5439664/ https://ncbi.nlm.nih.gov/pubmed/28531229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175463 |
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