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A Sortase A programmable phage display format for improved panning of Fab antibody libraries

Phage display of combinatorial antibody libraries is a versatile tool in the field of antibody engineering, with diverse applications including monoclonal antibody (mAb) discovery, affinity maturation, and humanization. To improve the selection efficiency of antibody libraries, we developed a new ph...

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Bibliographische Detailangaben
Veröffentlicht in:J Mol Biol
Hauptverfasser: Wilson, Henry D., Li, Xiuling, Peng, Haiyong, Rader, Christoph
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186506/
https://ncbi.nlm.nih.gov/pubmed/30213726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2018.09.003
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