A phage display approach for rapid antibody humanization: Designed combinatorial V gene libraries
The development of a new strategy for antibody humanization is described. This strategy incorporates key recognition sequences from the parental rodent antibody into a phage display-based selection strategy. The original sequences of the third complementarity-determining regions (CDRs) of heavy and...
שמור ב:
| הוצא לאור ב: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
1998
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21176/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9671778/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.15.8910 |
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