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A phage display approach for rapid antibody humanization: Designed combinatorial V gene libraries

The development of a new strategy for antibody humanization is described. This strategy incorporates key recognition sequences from the parental rodent antibody into a phage display-based selection strategy. The original sequences of the third complementarity-determining regions (CDRs) of heavy and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rader, Christoph, Cheresh, David A., Barbas, Carlos F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 1998
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC21176/
https://ncbi.nlm.nih.gov/pubmed/9671778
Etiketak: Etiketa erantsi
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