Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces.

We describe a method based on a phagemid vector with helper phage rescue for the construction and rapid analysis of combinatorial antibody Fab libraries. This approach should allow the generation and selection of many monoclonal antibodies. Antibody genes are expressed in concert with phage morphoge...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Kang, A S, Barbas, C F, Janda, K D, Benkovic, S J, Lerner, R A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51659/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1903540/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.10.4363
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