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Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces.

We describe a method based on a phagemid vector with helper phage rescue for the construction and rapid analysis of combinatorial antibody Fab libraries. This approach should allow the generation and selection of many monoclonal antibodies. Antibody genes are expressed in concert with phage morphoge...

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Détails bibliographiques
Auteurs principaux: Kang, A S, Barbas, C F, Janda, K D, Benkovic, S J, Lerner, R A
Format: Artigo
Langue:Inglês
Publié: 1991
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC51659/
https://ncbi.nlm.nih.gov/pubmed/1903540
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