Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces.
We describe a method based on a phagemid vector with helper phage rescue for the construction and rapid analysis of combinatorial antibody Fab libraries. This approach should allow the generation and selection of many monoclonal antibodies. Antibody genes are expressed in concert with phage morphoge...
সংরক্ষণ করুন:
| প্রকাশিত: | Proc Natl Acad Sci U S A |
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| প্রধান লেখক: | , , , , |
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
National Academy of Sciences
1991
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51659/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1903540/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.10.4363 |
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