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Structural Insights into the Eukaryotic Transcription Initiation Machinery

Eukaryotic gene transcription requires the assembly at the promoter of a large preinitiation complex (PIC) that includes RNA polymerase II (Pol II) and the general transcription factors TFIID, TFIIA, TFIIB, TFIIF, TFIIE, and TFIIH. The size and complexity of Pol II, TFIID, and T FIIH have precluded...

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Detalhes bibliográficos
Publicado no:Annu Rev Biophys
Main Authors: Nogales, Eva, Louder, Robert K., He, Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186020/
https://ncbi.nlm.nih.gov/pubmed/28532216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biophys-070816-033751
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