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Structural visualization of key steps in human transcription initiation

Eukaryotic transcription initiation requires the assembly of general transcription factors into a pre-initiation complex that ensures the accurate loading of RNA polymerase II at the transcription start site. The molecular mechanism and function of this assembly have remained elusive due to lack of...

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Main Authors: He, Yuan, Fang, Jie, Taatjes, Dylan J., Nogales, Eva
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612373/
https://ncbi.nlm.nih.gov/pubmed/23446344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11991
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