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Structural visualization of key steps in human transcription initiation

Eukaryotic transcription initiation requires the assembly of general transcription factors into a pre-initiation complex that ensures the accurate loading of RNA polymerase II at the transcription start site. The molecular mechanism and function of this assembly have remained elusive due to lack of...

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Detalhes bibliográficos
Main Authors: He, Yuan, Fang, Jie, Taatjes, Dylan J., Nogales, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612373/
https://ncbi.nlm.nih.gov/pubmed/23446344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11991
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