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Structural Insights into the Eukaryotic Transcription Initiation Machinery
Eukaryotic gene transcription requires the assembly at the promoter of a large preinitiation complex (PIC) that includes RNA polymerase II (Pol II) and the general transcription factors TFIID, TFIIA, TFIIB, TFIIF, TFIIE, and TFIIH. The size and complexity of Pol II, TFIID, and T FIIH have precluded...
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| 發表在: | Annu Rev Biophys |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6186020/ https://ncbi.nlm.nih.gov/pubmed/28532216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biophys-070816-033751 |
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