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Sorafenib resistance in hepatocarcinoma: role of hypoxia-inducible factors
Sorafenib, a multikinase inhibitor with antiproliferative, antiangiogenic, and proapoptotic properties, constitutes the only effective first-line drug approved for the treatment of advanced hepatocellular carcinoma (HCC). Despite its capacity to increase survival in HCC patients, its success is quit...
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| Pubblicato in: | Exp Mol Med |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6185986/ https://ncbi.nlm.nih.gov/pubmed/30315182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0159-1 |
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