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FEMALE SEX HORMONES ALTER THE METABOLIC IMPACT OF HEPATIC RICTOR DELETION

Rapamycin is an immunosuppressant and anticancer drug that extends lifespan in model organisms including mice, but side effects including metabolic disruption may limit its wide-scale use for diseases of aging. We have previously found that many side effects of rapamycin may be mediated by “off-targ...

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Podrobná bibliografie
Vydáno v:Innov Aging
Hlavní autoři: Arriola Apelo, S.I., Pumper, C.P., Cummings, N., Lin, A., Baar, E.L., Lamming, D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6184547/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.3091
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