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FEMALE SEX HORMONES ALTER THE METABOLIC IMPACT OF HEPATIC RICTOR DELETION
Rapamycin is an immunosuppressant and anticancer drug that extends lifespan in model organisms including mice, but side effects including metabolic disruption may limit its wide-scale use for diseases of aging. We have previously found that many side effects of rapamycin may be mediated by “off-targ...
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| Publicado no: | Innov Aging |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6184547/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.3091 |
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