siAbasic: a comprehensive database for potent siRNA-6Ø sequences without off-target effects

Small interfering RNA (siRNA) is widely used to specifically silence target gene expression, but its microRNA (miRNA)-like function inevitably suppresses hundreds of off-targets. Recently, complete elimination of the off-target repression has been achieved by introducing an abasic nucleotide to the...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Database (Oxford)
Main Authors: Park, Jongyeun, Ahn, Seung Hyun, Cho, Kwang Moon, Gu, Dowoon, Jang, Eun-Sook, Chi, Sung Wook
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6183071/
https://ncbi.nlm.nih.gov/pubmed/30321353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/database/bay109
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki