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siAbasic: a comprehensive database for potent siRNA-6Ø sequences without off-target effects

Small interfering RNA (siRNA) is widely used to specifically silence target gene expression, but its microRNA (miRNA)-like function inevitably suppresses hundreds of off-targets. Recently, complete elimination of the off-target repression has been achieved by introducing an abasic nucleotide to the...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Database (Oxford)
Päätekijät: Park, Jongyeun, Ahn, Seung Hyun, Cho, Kwang Moon, Gu, Dowoon, Jang, Eun-Sook, Chi, Sung Wook
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6183071/
https://ncbi.nlm.nih.gov/pubmed/30321353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/database/bay109
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