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siAbasic: a comprehensive database for potent siRNA-6Ø sequences without off-target effects
Small interfering RNA (siRNA) is widely used to specifically silence target gene expression, but its microRNA (miRNA)-like function inevitably suppresses hundreds of off-targets. Recently, complete elimination of the off-target repression has been achieved by introducing an abasic nucleotide to the...
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| Publicado no: | Database (Oxford) |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6183071/ https://ncbi.nlm.nih.gov/pubmed/30321353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/database/bay109 |
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