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Pharmacokinetics, Pharmacodynamics and Pharmacogenetics of Tacrolimus in Kidney Transplantation
BACKGROUND: Tacrolimus (Tac, or FK506), a calcineurin inhibitor (CNI), is the first-line immu-nosuppressant which consists of the footstone as immunosuppressive regimens in kidney transplantation. However, the drug toxicity and the significant differences of pharmacokinetics (PK) and pharmacodynam-i...
Gespeichert in:
| Veröffentlicht in: | Curr Drug Metab |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Bentham Science Publishers
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6182932/ https://ncbi.nlm.nih.gov/pubmed/29380698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1389200219666180129151948 |
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