Population pharmacokinetic and pharmacogenetic analysis of tacrolimus in paediatric liver transplant patients

AIMS: To build a population pharmacokinetic model that describes the apparent clearance of tacrolimus and the potential demographic, clinical and genetically controlled factors that could lead to inter-patient pharmacokinetic variability within children following liver transplantation. METHODS: The...

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Hauptverfasser: Abdel Jalil, Mariam H, Hawwa, Ahmed F, McKiernan, Patrick J, Shields, Michael D, McElnay, James C
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2014
Schlagworte:
Pharmacokinetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895354/
https://ncbi.nlm.nih.gov/pubmed/23738951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12174
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