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Population pharmacokinetics and pharmacogenetics of once daily tacrolimus formulation in stable liver transplant recipients
PURPOSE: The once daily formulation of tacrolimus is an important immunosuppressive drug. Interpatient variability in metabolism has been related to genetic variation in CYP3A4 and CYP3A5. However, in liver transplantation, both donor and recipient genotypes may affect pharmacokinetics. The primary...
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Publicado no: | Eur J Clin Pharmacol |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer Berlin Heidelberg
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4713720/ https://ncbi.nlm.nih.gov/pubmed/26521259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-015-1963-3 |
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