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Comparison of the Impact of Pharmacogenetic Variability on the PK of Slow Release and Immediate Release Tacrolimus Formulations

Tacrolimus-modified release formulations allow for once-daily dosing, and adherence is better compared to the twice-daily immediate release formulation. When patients are switched from one formulation to another, variable changes in drug concentrations are observed. Current data suggest that the cha...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: van Gelder, Teun, Etsouli, Oumaima, Moes, Dirk Jan, Swen, Jesse J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7602647/
https://ncbi.nlm.nih.gov/pubmed/33076474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11101205
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