Explaining variability in ciclosporin exposure in adult kidney transplant recipients

PURPOSE: Optimal ciclosporin A (CsA) exposure in kidney transplant recipients is difficult to attain because of variability in CsA pharmacokinetics. A better understanding of the variability in CsA exposure could be a good means of individualizing therapy. Specifically, genetic variability in genes...

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Autori principali: Press, Rogier R., Ploeger, Bart A., den Hartigh, Jan, van der Straaten, T., van Pelt, Hans, Danhof, Meindert, de Fijter, Hans, Guchelaar, Henk-Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2010
Soggetti:
Pharmacogenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868991/
https://ncbi.nlm.nih.gov/pubmed/20354687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-010-0810-9
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