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Application of the Convection–Dispersion Equation to Modelling Oral Drug Absorption

Models of systemic drug absorption after oral administration are frequently based on a direct or a delayed first-order rate process. In practice, the use of the first-order approach to predict drug concentrations in blood plasma frequently yields a considerable mismatch between predicted and measure...

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Detalhes bibliográficos
Main Authors: Freijer, Jan I., Post, Teun M., Ploeger, Bart A., DeJongh, Joost, Danhof, Meindert
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799010/
https://ncbi.nlm.nih.gov/pubmed/17024551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11538-006-9122-8
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