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Influence of ABCB1 polymorphisms and haplotypes on tacrolimus nephrotoxicity and dosage requirements in children with liver transplant

AIMS: The aim of this study was to investigate the influence of genetic polymorphisms in ABCB1 on the incidence of nephrotoxicity and tacrolimus dosage-requirements in paediatric patients following liver transplantation. METHODS: Fifty-one paediatric liver transplant recipients receiving tacrolimus...

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Detalhes bibliográficos
Main Authors: Hawwa, Ahmed F, McKiernan, Patrick J, Shields, Michael, Millership, Jeff S, Collier, Paul S, McElnay, James C
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766481/
https://ncbi.nlm.nih.gov/pubmed/19740399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03461.x
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