Regionally clustered ABCC8 polymorphisms in a prospective cohort predict cerebral edema and outcome in severe traumatic brain injury

OBJECTIVE: ABCC8 encodes sulfonylurea-receptor-1, a key regulatory protein of cerebral edema in many neurological disorders including traumatic brain injury (TBI). Sulfonylurea-receptor-1 inhibition has been promising in ameliorating cerebral edema in clinical trials. We evaluated whether ABCC8 tag-...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Neurol Neurosurg Psychiatry
Main Authors: Jha, Ruchira M., Koleck, Theresa A., Puccio, Ava M., Okonkwo, David O., Park, Seo-Young, Zusman, Benjamin E., Clark, Robert S.B., Shutter, Lori A., Wallisch, Jessica S., Empey, Philip E., Kochanek, Patrick M., Conley, Yvette P.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181785/
https://ncbi.nlm.nih.gov/pubmed/29674479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp-2017-317741
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares