Sulfonylurea Receptor-1: A Novel Biomarker for Cerebral Edema in Severe Traumatic Brain Injury

OBJECTIVE: Cerebral edema(CE) is a key poor prognosticator in TBI. There are no biomarkers identifying patients at-risk, or guiding mechanistically-precise therapies. Sulfonylurea Receptor-1(Sur1) is upregulated only after brain injury, causing edema in animal studies. We hypothesized that Sur1 is m...

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Detalhes bibliográficos
Publicado no:Crit Care Med
Main Authors: Jha, Ruchira M., Puccio, Ava, Chou, Sherry Hsiang Yi, Chang, Chung-Chou H., Wallisch, Jessica, Molyneaux, Bradley J., Zusman, Benjamin E, Shutter, Lori A, Poloyac, Samuel M., Janesko-Feldman, Keri L, Okonkwo, David O, Kochanek, Patrick M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550829/
https://ncbi.nlm.nih.gov/pubmed/27845954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000002079
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