Downstream TRPM4 Polymorphisms Are Associated with Intracranial Hypertension and Statistically Interact with ABCC8 Polymorphisms in a Prospective Cohort of Severe Traumatic Brain Injury

Sulfonylurea-receptor-1(SUR1) and its associated transient-receptor-potential cation channel subfamily-M (TRPM4) channel are key contributors to cerebral edema and intracranial hypertension in traumatic brain injury (TBI) and other neurological disorders. Channel inhibition by glyburide is clinicall...

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Veröffentlicht in:J Neurotrauma
Hauptverfasser: Jha, Ruchira M., Desai, Shashvat M., Zusman, Benjamin E., Koleck, Theresa A., Puccio, Ava M., Okonkwo, David O., Park, Seo-Young, Shutter, Lori A., Kochanek, Patrick M., Conley, Yvette P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc., publishers 2019
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551973/
https://ncbi.nlm.nih.gov/pubmed/30484364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2018.6124
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