Metformin Increases Cardiac Rupture After Myocardial Infarction via the AMPK-MTOR/PGC-1α Signaling Pathway in Rats with Acute Myocardial Infarction

BACKGROUND: Cardiac rupture often occurs after acute myocardial infarction due to complex and unclear pathogenesis. This study investigated whether metformin increases the incidence of cardiac rupture after myocardial infarction through the AMPK-MTOR/PGC-1α signaling pathway. MATERIAL/METHODS: An ac...

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Udgivet i:Med Sci Monit
Main Authors: Hua, Jinghai, Liu, Zhanghua, Liu, Zuheng, An, Dongqi, Lai, Wenyan, Zhan, Qiong, Zeng, Qingchun, Ren, Hao, Xu, Dingli
Format: Artigo
Sprog:Inglês
Udgivet: International Scientific Literature, Inc. 2018
Fag:
Animal Study
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180847/
https://ncbi.nlm.nih.gov/pubmed/30275441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.910930
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