Metformin Increases Cardiac Rupture After Myocardial Infarction via the AMPK-MTOR/PGC-1α Signaling Pathway in Rats with Acute Myocardial Infarction

BACKGROUND: Cardiac rupture often occurs after acute myocardial infarction due to complex and unclear pathogenesis. This study investigated whether metformin increases the incidence of cardiac rupture after myocardial infarction through the AMPK-MTOR/PGC-1α signaling pathway. MATERIAL/METHODS: An ac...

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Bibliografiska uppgifter
I publikationen:Med Sci Monit
Huvudupphovsmän: Hua, Jinghai, Liu, Zhanghua, Liu, Zuheng, An, Dongqi, Lai, Wenyan, Zhan, Qiong, Zeng, Qingchun, Ren, Hao, Xu, Dingli
Materialtyp: Artigo
Språk:Inglês
Publicerad: International Scientific Literature, Inc. 2018
Ämnen:
Animal Study
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180847/
https://ncbi.nlm.nih.gov/pubmed/30275441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.910930
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