Metformin Increases Cardiac Rupture After Myocardial Infarction via the AMPK-MTOR/PGC-1α Signaling Pathway in Rats with Acute Myocardial Infarction

BACKGROUND: Cardiac rupture often occurs after acute myocardial infarction due to complex and unclear pathogenesis. This study investigated whether metformin increases the incidence of cardiac rupture after myocardial infarction through the AMPK-MTOR/PGC-1α signaling pathway. MATERIAL/METHODS: An ac...

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Dettagli Bibliografici
Pubblicato in:Med Sci Monit
Autori principali: Hua, Jinghai, Liu, Zhanghua, Liu, Zuheng, An, Dongqi, Lai, Wenyan, Zhan, Qiong, Zeng, Qingchun, Ren, Hao, Xu, Dingli
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Scientific Literature, Inc. 2018
Soggetti:
Animal Study
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180847/
https://ncbi.nlm.nih.gov/pubmed/30275441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.910930
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