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Metformin Increases Cardiac Rupture After Myocardial Infarction via the AMPK-MTOR/PGC-1α Signaling Pathway in Rats with Acute Myocardial Infarction

BACKGROUND: Cardiac rupture often occurs after acute myocardial infarction due to complex and unclear pathogenesis. This study investigated whether metformin increases the incidence of cardiac rupture after myocardial infarction through the AMPK-MTOR/PGC-1α signaling pathway. MATERIAL/METHODS: An ac...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Hua, Jinghai, Liu, Zhanghua, Liu, Zuheng, An, Dongqi, Lai, Wenyan, Zhan, Qiong, Zeng, Qingchun, Ren, Hao, Xu, Dingli
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180847/
https://ncbi.nlm.nih.gov/pubmed/30275441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.910930
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