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Knockdown of hypocretin attenuates extended access of cocaine self-administration in rats
The hypocretin/orexin (HCRT) neuropeptide system regulates feeding, arousal state, stress responses, and reward, especially under conditions of enhanced motivational relevance. In particular, HCRT neurotransmission facilitates drug-seeking behavior in circumstances that demand increased effort and/o...
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| Publié dans: | Neuropsychopharmacology |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer International Publishing
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6180106/ https://ncbi.nlm.nih.gov/pubmed/29703996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0054-4 |
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