Nrf3 promotes UV-induced keratinocyte apoptosis through suppression of cell adhesion

The transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) is a key regulator of the cellular stress response, but the biological functions of the related Nrf3 protein are largely unknown. Here we demonstrate a novel pro-apoptotic function of Nrf3 in mouse and human keratinocytes. I...

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Udgivet i:Cell Death Differ
Main Authors: Siegenthaler, Beat, Defila, Claudia, Muzumdar, Sukalp, Beer, Hans-Dietmar, Meyer, Michael, Tanner, Sandra, Bloch, Wilhelm, Blank, Volker, Schäfer, Matthias, Werner, Sabine
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6179989/
https://ncbi.nlm.nih.gov/pubmed/29487353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0074-y
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