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A Glutathione-Nrf2-Thioredoxin Cross-Talk Ensures Keratinocyte Survival and Efficient Wound Repair

The tripeptide glutathione is the most abundant cellular antioxidant with high medical relevance, and it is also required as a co-factor for various enzymes involved in the detoxification of reactive oxygen species and toxic compounds. However, its cell-type specific functions and its interaction wi...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Genet
Hauptverfasser: Telorack, Michèle, Meyer, Michael, Ingold, Irina, Conrad, Marcus, Bloch, Wilhelm, Werner, Sabine
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726503/
https://ncbi.nlm.nih.gov/pubmed/26808544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005800
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