Loss of serum response factor in keratinocytes results in hyperproliferative skin disease in mice

The transcription factor serum response factor (SRF) plays a crucial role in the development of several organs. However, its role in the skin has not been explored. Here, we show that keratinocytes in normal human and mouse skin expressed high levels of SRF but that SRF expression was strongly downr...

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Detalhes bibliográficos
Main Authors: Koegel, Heidi, von Tobel, Lukas, Schäfer, Matthias, Alberti, Siegfried, Kremmer, Elisabeth, Mauch, Cornelia, Hohl, Daniel, Wang, Xiao-Jing, Beer, Hans-Dietmar, Bloch, Wilhelm, Nordheim, Alfred, Werner, Sabine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662566/
https://ncbi.nlm.nih.gov/pubmed/19307725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI37771
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