Loss of serum response factor in keratinocytes results in hyperproliferative skin disease in mice

The transcription factor serum response factor (SRF) plays a crucial role in the development of several organs. However, its role in the skin has not been explored. Here, we show that keratinocytes in normal human and mouse skin expressed high levels of SRF but that SRF expression was strongly downr...

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Hlavní autoři: Koegel, Heidi, von Tobel, Lukas, Schäfer, Matthias, Alberti, Siegfried, Kremmer, Elisabeth, Mauch, Cornelia, Hohl, Daniel, Wang, Xiao-Jing, Beer, Hans-Dietmar, Bloch, Wilhelm, Nordheim, Alfred, Werner, Sabine
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2009
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662566/
https://ncbi.nlm.nih.gov/pubmed/19307725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI37771
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