A carregar...
Mechanical cues control mutant p53 stability through a Mevalonate/RhoA axis
Tumour-associated p53 missense mutants act as driver oncogenes impacting cancer progression, metastatic potential and drug resistance (Gain-of-Function, GOF)1. Mutant p53 protein stabilization is a prerequisite for GOF manifestation, however it does not represent an intrinsic property of p53 mutants...
Na minha lista:
| Publicado no: | Nat Cell Biol |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6179142/ https://ncbi.nlm.nih.gov/pubmed/29255172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-017-0009-8 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|