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Mutant p53: One, No One, and One Hundred Thousand
Encoded by the mutated variants of the TP53 tumor suppressor gene, mutant p53 proteins are getting an increased experimental support as active oncoproteins promoting tumor growth and metastasis. p53 missense mutant proteins are losing their wild-type tumor suppressor activity and acquire oncogenic p...
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| 發表在: | Front Oncol |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Frontiers Media S.A.
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4685664/ https://ncbi.nlm.nih.gov/pubmed/26734571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00289 |
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