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Mutant p53: One, No One, and One Hundred Thousand

Encoded by the mutated variants of the TP53 tumor suppressor gene, mutant p53 proteins are getting an increased experimental support as active oncoproteins promoting tumor growth and metastasis. p53 missense mutant proteins are losing their wild-type tumor suppressor activity and acquire oncogenic p...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Oncol
Prif Awduron: Walerych, Dawid, Lisek, Kamil, Del Sal, Giannino
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685664/
https://ncbi.nlm.nih.gov/pubmed/26734571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00289
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