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Mutant p53: One, No One, and One Hundred Thousand

Encoded by the mutated variants of the TP53 tumor suppressor gene, mutant p53 proteins are getting an increased experimental support as active oncoproteins promoting tumor growth and metastasis. p53 missense mutant proteins are losing their wild-type tumor suppressor activity and acquire oncogenic p...

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Bibliografiska uppgifter
I publikationen:Front Oncol
Huvudupphovsmän: Walerych, Dawid, Lisek, Kamil, Del Sal, Giannino
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685664/
https://ncbi.nlm.nih.gov/pubmed/26734571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00289
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