Protein Engineering Reveals Mechanisms of Functional Amyloid Formation in Pseudomonas aeruginosa Biofilms

Amyloids are typically associated with neurodegenerative diseases, but recent research demonstrates that several bacteria utilize functional amyloid fibrils to fortify the biofilm extracellular matrix and thereby resist antibiotic treatments. In Pseudomonas aeruginosa, these fibrils are composed pre...

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Pubblicato in:J Mol Biol
Autori principali: Bleem, Alissa, Christiansen, Gunna, Madsen, Daniel J., Maric, Hans, Strømgaard, Kristian, Bryers, James D., Daggett, Valerie, Meyer, Rikke L., Otzen, Daniel E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178955/
https://ncbi.nlm.nih.gov/pubmed/29964047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2018.06.043
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