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Protein Engineering Reveals Mechanisms of Functional Amyloid Formation in Pseudomonas aeruginosa Biofilms

Amyloids are typically associated with neurodegenerative diseases, but recent research demonstrates that several bacteria utilize functional amyloid fibrils to fortify the biofilm extracellular matrix and thereby resist antibiotic treatments. In Pseudomonas aeruginosa, these fibrils are composed pre...

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Bibliografiske detaljer
Udgivet i:J Mol Biol
Main Authors: Bleem, Alissa, Christiansen, Gunna, Madsen, Daniel J., Maric, Hans, Strømgaard, Kristian, Bryers, James D., Daggett, Valerie, Meyer, Rikke L., Otzen, Daniel E.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178955/
https://ncbi.nlm.nih.gov/pubmed/29964047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2018.06.043
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