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The current state of GPCR‐based drug discovery to treat metabolic disease

One approach of modern drug discovery is to identify agents that enhance or diminish signal transduction cascades in various cell types and tissues by modulating the activity of GPCRs. This strategy has resulted in the development of new medicines to treat many conditions, including cardiovascular d...

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Библиографические подробности
Опубликовано в: :Br J Pharmacol
Главные авторы: Sloop, Kyle W, Emmerson, Paul J, Statnick, Michael A, Willard, Francis S
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177613/
https://ncbi.nlm.nih.gov/pubmed/29394497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14157
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