Role of apurinic/apyrimidinic nucleases in the regulation of homologous recombination in myeloma: mechanisms and translational significance

We have previously reported that homologous recombination (HR) is dysregulated in multiple myeloma (MM) and contributes to genomic instability and development of drug resistance. We now demonstrate that base excision repair (BER) associated apurinic/apyrimidinic (AP) nucleases (APEX1 and APEX2) cont...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Blood Cancer J
Egile Nagusiak: Kumar, Subodh, Talluri, Srikanth, Pal, Jagannath, Yuan, Xiaoli, Lu, Renquan, Nanjappa, Puru, Samur, Mehmet K., Munshi, Nikhil C., Shammas, Masood A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177467/
https://ncbi.nlm.nih.gov/pubmed/30301882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-018-0129-9
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